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INSERM UMR 1063 : Stress oxydant et pathologies métaboliques (SOPAM)

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    • Agouni A, Mostefai HA, Lagrue A-H, Sladkova M, Rouet P, Desmoulin F, Pechanova O, Martinez MC, Andriantsitohaina R. Paradoxical effect of non-alcoholic red-wine polyphenols extract, Provinols™, in the regulation of cyclooxygenases in vessels from Zucker Fatty rats (fa/fa). Oxid Med Cell Longev 2017;2017:8536910.
    • Amosse J, Martinez MC, Le Lay S. Extracellular vesicles and cardiovascular disease therapy. Stem Cell Investig 2017;4:102
    • Bironneau V, Goupil F, Ducluzeau PH, Le Vaillant M, Abraham P, Henni S, Dubois S, Paris A, Priou P, Meslier N, Sanguin C, Trzepizur W, Andriantsitohaina R,  Martinez MC, Gagnadoux F. Association between obstructive sleep apnea severity and endothelial dysfunction in patients with type 2 diabetes. Cardiovasc Diabetol 2017;16:39.
    • Blasco H, Veyrat-Durebex C, Bocca C, Patin F, Vourc'h P, Kouassi Nzoughet J, Lenaers G, Andres CR, Simard G, Corcia P, Reynier P. Lipidomics reveals cerebrospinal-fluid signatures of ALS. Sci Rep. 2017;7:17652.
    • Chao de la Barca JM, Simard G, Sarzi E, Chaumette T, Rousseau G, Chupin S, Gadras C, Tessier L, Ferré M, Chevrollier A, Desquiret-Dumas V, Gueguen N, Leruez S, Verny C, Miléa D, Bonneau D, Amati-Bonneau P, Procaccio V, Hamel C, Lenaers G, Reynier P, Prunier-Mirebeau D. Targeted metabolomics reveals early dominant optic atrophy signature in optic nerves of opa1delttag/+ mice. Invest Ophthalmol Vis Sci. 2017;58:812-820.
    • Dayoub O, Le Lay S, Soleti R, Clere N, Hilairet G, Dubois S, Gagnadoux F, Boursier J, Martínez MC, Andriantsitohaina R. Estrogen receptor α/HDAC/NFAT axis for delphinidin effects on proliferation and differentiation of T lymphocytes from patients with cardiovascular risks. Sci Reports 2017;7:9378.
    • de la Barca JMC, Boueilh T, Simard G, Boucret L, Ferré-L'Hotellier V, Tessier L, Gadras C, Bouet PE, Descamps P, Procaccio V, Reynier P, May-Panloup P. Targeted metabolomics reveals reduced levels of polyunsaturated choline plasmalogens and a smaller dimethylarginine/arginine ratio in the follicular fluid of patients with a diminished ovarian reserve. Hum Reprod. 2017;32:2269-2278.
    • de la Barca JMC, Huang NT, Jiao H, Tessier L, Gadras C, Simard G, Natoli R, Tcherkez G, Reynier P, Valter K. Retinal metabolic events in preconditioning light stress as revealed by wide-spectrum targeted metabolomics. Metabolomics. 2017;13:22.
    • Durcin M, Fleury A, Taillebois E, Hilairet G, Krupova Z, Henry C, Truchet S, Trötzmüller M, Köfeler H, Mabilleau G, Hue O, Andriantsitohaina R, Martin P, Le Lay S. Characterization of adipocyte-derived EV subtypes identifies distinct protein and lipid signatures for microvesicles and exosomes. J Extracell Ves 2017;6:1305677.
    • Esnault C, Leiber D, Toffano-Nioche C, Tanfin Z, Virolle MJ. Another example of enzymatic promiscuity: the polyphosphate kinase of Streptomyces lividans is endowed with phospholipase D activity. Appl Microbiol Biotechnol. 2017;101:139-145.
    • Gagnadoux F, Jouvenot M, Meslier N, Priou P, Trzepizur W. [Therapeutic alternatives to continuous positive airway pressure for obstructive sleep apnea-hypopnea syndrome]. Presse Med. 2017;46:432-437.
    • Gagnadoux F, Nguyen XL, Le Vaillant M, Priou P, Meslier N, Eberlein A, Kun-Darbois JD, Chaufton C, Villiers B, Levy M, Trzépizur W, Launois S. Comparison of titrable thermoplastic versus custom-made mandibular advancement device for the treatment of obstructive sleep apnoea. Respir Med. 2017;131:35-42.
    • Gagnadoux F, Pépin JL, Vielle B, Bironneau V, Chouet-Girard F, Launois S, Meslier N, Meurice JC, Nguyen XL, Paris A, Priou P, Tamisier R, Trzepizur W, Goupil F, Fleury B. Impact of mandibular advancement therapy on endothelial function in severe obstructive sleep apnea. Am J Respir Crit Care Med. 2017; 195:1244-1252
    • Gagnadoux F, Pépin JL, Vielle B, Bironneau V, Chouet-Girard F, Launois S, Meslier N, Meurice JC, Nguyen XL, Paris A, Priou P, Tamisier R, Trzepizur W, Goupil F, Fleury B. Reply to the choice of indicators for OSA treatment outcome evaluation: a matter of time-dependent response? Am J Respir Crit Care Med. 2017;196:1357-1359.
    • Gagnadoux F, Pevernagie D, Jennum P, Lon N, Loiodice C, Tamisier R, van Mierlo P, Trzepizur W, Neddermann M, Machleit A, Jasko J, Pépin JL. Validation of the system one remstar auto a-flex for obstructive sleep apnea treatment and detection of residual apnea-hypopnea index: a European randomized trial. J Clin Sleep Med. 2017;13:283-290.
    • Gagnadoux F, Priou P, Urban T, Meslier N, Trzepizur W. [Sleep apneas, metabolic syndrome and cardiovascular risk: Data from the Pays de la Loire sleep cohort]. Rev Pneumol Clin. 2017;73:299-305.
    • Gagnadoux F, Priou P, Meslier N, Trzepizur W. Effects of sleep apnoea therapy on blood pressure and metabolism: a CPAP sex gap? Eur Respir J. 2017;50(2).
    • Gille T, Didier M, Boubaya M, Moya L, Sutton A, Carton Z, Baran-Marszak F, Sadoun-Danino D, Israël-Biet D, Cottin V, Gagnadoux F, Crestani B, d'Ortho MP, Brillet PY, Valeyre D, Nunes H, Planès C; collaborators. Obstructive sleep apnoea and related comorbidities in incident idiopathic pulmonary fibrosis. Eur Respir J. 2017;49(6).
    • Kouassi Nzoughet J, Bocca C, Simard G, Prunier-Mirebeau D, Chao de la Barca JM, Bonneau D, Procaccio V, Prunier F, Lenaers G, Reynier P. A non-targeted UHPLC-HRMS metabolomics pipeline for metabolite identification; application to cardiac remote ischemic preconditioning. Anal Chem. 2017;89:2138-2146.
    • Leclercq G, Elie-Caille C, Leiber D, Hodler L, Laurent G, Lesniewska E, Tanfin Z, Jacquot Y. ERα dimerization: A key factor for the weak estrogen activity of an ERα modulators unable to compete with estradiol in binding assays. J Recept Sig Transd 2017 37:149-166.
    • Leonetti D, Soleti R, Clere N, Vergori L, Jacques C, Duluc L, Dourguia C, Martínez MC, Andriantsitohaina R. Estrogen receptor α participates to the beneficial effect of red wine polyphenols in a mouse model of obesity-related disorders. Front Pharmacol 2017;7:529.
    • Lim L, Palayer M, Bruneau A, Letournel F, Le Maréchal C, Simard G, Reynier P, Homedan C, Nadaj-Pakleza A. Myoadenylate deaminase deficiency: a frequent cause of muscle pain A case detected by exercise testing. Ann Biol Clin (Paris). 2017;75:445-449.
    • Marche P, Dubois S, Abraham P, Parot-Schinkel E, Gascoin L, Humeau-Heurtier A, Ducluzeau PH, Mahe G. Neurovascular microcirculatory vasodilation mediated by C-fibers and Transient receptor potential vanilloid-type-1 channels (TRPV 1) is impaired in type 1 diabetes. Sci Rep. 2017;7:44322.
    • Martinez MC, Andriantsitohaina R. Extracellular vesicles and metabolic syndrome. Circ Res 2017;120:1674-1686.
    • Ouedraogo V, Soleti R, Signolet I, Diawa M, Hallabd M, Samba A, Andriantsitohaina R, Baa A, Lefthériotis G. Impact of sickle cell trait on arterial stiffness in African subjects. J Med Vasc 2017;42:14-20.
    • Pelosi M, Testet E, Le Lay S, Dugail I, Tang X, Mabilleau G, Hamel Y, Madrange M, Blanc T, Odent T, McMullen TPW, Alfò M, Brindley DN, de Lonlay P. Normal human adipose tissue functions and differentiation in patients with biallelic LPIN1 inactivating mutations. J Lipid Res. 2017;58:2348-2364.
    • Pepin JL, Gagnadoux F, Foote A, Vicars R, Ogra B, Viot-Blanc V, Benmerad M, D'Ortho MP, Tamisier R. Combination of obstructive sleep apnoea and insomnia treated by continuous positive airway pressure with the SensAwake pressure relief technology to assist sleep: a randomised cross-over trial protocol. BMJ Open. 2017;7:e015836.
    • Priou P, Trzepizur W, Meslier N, Gagnadoux F. [Update on the respiratory management of patients with chronic neuromuscular disease]. Rev Pneumol Clin. 2017;73:316-322.
    • Recoquillon S, Gómez-Guzmán M, Rodier M, Koffi C, Nitiéma M, Gagnadoux F, Martinez MC, Andriantsitohaina R. Non-muscular myosin light chain kinase triggers intermittent hypoxia-induced interleukin-6 release, endothelial dysfunction and permeability. Sci Reports 2017;7:13664.
    • Rousseau G, Signolet I, Denis MC, de la Barca JMC, Mahieu R, Letournel F, Reynier P, Simard G. 5-Oxoprolinuria in hyperammonemic encephalopathy: Coincidence or worsening factor? Clin Biochem. 2017;50):1115-1117.
    • Russomanno G, Corbi G, Manzo V, Ferrara N, Rengo G, Puca AA, Latte S, Carrizzo A, Calabrese MC, Andriantsitohaina R, Filippelli W, Vecchione C, Filippelli A, Conti V. The anti-ageing molecule sirt1 mediates beneficial effects of cardiac rehabilitation. Immun Ageing. 2017;14:7.
    • Safiedeen Z, Rodríguez-Gómez I, Vergori L, Soleti R, Vaithilingam D, Imene Douma I, Agouni A, Leiber D, Dubois S, Simard G, Zibara K, Andriantsitohaina R, Martínez MC. Temporal cross-talk between endoplasmic reticulum and mitochondria regulates oxidative stress and mediates microparticle-induced endothelial dysfunction. Antioxid Redox Signal 2017;26:15-27.
    • Trenteseaux C, Gaston At, Aguesse A, Poupeau G, Coppet P, Amarger V, Andriantsitohaina R, Khallou-Laschet J, Krempf M, Nobecourt-Dupuy E, Ouguerram K. Perinatal hypercholesterolemia exacerbates atherosclerosis lesions in offspring by altering metabolism of trimethylamine-N-oxide and bile acids. Arterioscler Thromb Vasc Biol 2017;37:2053-2063.
    • Trzepizur W, Khalyfa A, Qiao Z, Popko B, Gozal D. Integrated stress response activation by sleep fragmentation during late gestation in mice leads to emergence of adverse metabolic phenotype in offspring. Metabolism 2017;69:188-198.
    • Trzepizur W, Priou P, Meslier N, Urban T, Martínez MC, Andriantsitohaina R, Gagnadoux F. [Vascular dysfunction in obstructive sleep apnoea: Implication of microparticules]. Rev Pneumol Clin. 2017;73:306-308.